163 research outputs found
Gimballess Inertial Navigation Systems. Semi- Annual Progress Report, 1 Nov. 1964 - 30 Apr. 1965
Accelerometers for sensing angular velocity in gimballess inertial navigation syste
Modeling and Analysis of Power Processing Systems
The feasibility of formulating a methodology for the modeling and analysis of aerospace electrical power processing systems is investigated. It is shown that a digital computer may be used in an interactive mode for the design, modeling, analysis, and comparison of power processing systems
Spectroscopic Detection of Carbon Monoxide in Two Late-type T Dwarfs
M band spectra of two late-type T dwarfs, 2MASS J09373487+2931409, and Gliese
570D, confirm evidence from photometry that photospheric CO is present at
abundance levels far in excess of those predicted from chemical equilibrium.
These new and unambiguous detections of CO, together with an earlier
spectroscopic detection of CO in Gliese 229B and existing M band photometry of
a large selection of T dwarfs, suggest that vertical mixing in the photosphere
drives the CO abundance out of chemical equilibrium and is a common, and likely
universal feature of mid-to-late type T dwarfs. The M band spectra allow
determinations of the time scale of vertical mixing in the atmosphere of each
object, the first such measurements of this important parameter in late T
dwarfs. A detailed analysis of the spectral energy distribution of 2MASS
J09373487+2931409 results in the following values for metallicity, temperature,
surface gravity, and luminosity: [M/H]~-0.3, T_eff=925-975K, log g=5.20-5.47,
log L/L_sun=-5.308 +/- 0.027. The age is 3-10 Gyr and the mass is in the range
45-69 M_Jup.Comment: 36 pages incl. 12 figures and 3 tables, accepted by Ap
Atmospheric Chemistry in Giant Planets, Brown Dwarfs, and Low-Mass Dwarf Stars II. Sulfur and Phosphorus
Thermochemical equilibrium and kinetic calculations are used to model sulfur
and phosphorus chemistry in giant planets, brown dwarfs, and extrasolar giant
planets (EGPs). The chemical behavior of individual S- and P-bearing gases and
condensates is determined as a function of pressure, temperature, and
metallicity. The results are independent of particular model atmospheres and,
in principle, the equilibrium composition along the pressure-temperature
profile of any object can be determined. Hydrogen sulfide (H2S) is the dominant
S-bearing gas throughout substellar atmospheres and approximately represents
the atmospheric sulfur inventory. Silicon sulfide (SiS) is a potential tracer
of weather in substellar atmospheres. Disequilibrium abundances of phosphine
(PH3) approximately representative of the total atmospheric phosphorus
inventory are expected to be mixed upward into the observable atmospheres of
giant planets and T dwarfs. In hotter objects, several P-bearing gases (e.g.,
P2, PH3, PH2, PH, HCP) become increasingly important at high temperatures.Comment: 38 pages, 8 figures, accepted for Astrophysical Journa
Solubility of Rock in Steam Atmospheres of Planets
Extensive experimental studies show that all major rock-forming elements (e.g., Si, Mg, Fe, Ca, Al, Na, K) dissolve in steam to a greater or lesser extent. We use these results to compute chemical equilibrium abundances of rocky-element-bearing gases in steam atmospheres equilibrated with silicate magma oceans. Rocky elements partition into steam atmospheres as volatile hydroxide gases (e.g., Si(OH)4, Mg(OH)2, Fe(OH)2, Ni(OH)2, Al(OH)3, Ca(OH)2, NaOH, KOH) and via reaction with HF and HCl as volatile halide gases (e.g., NaCl, KCl, CaFOH, CaClOH, FAl(OH)2) in much larger amounts than expected from their vapor pressures over volatile-free solid or molten rock at high temperatures expected for steam atmospheres on the early Earth and hot rocky exoplanets. We quantitatively compute the extent of fractional vaporization by defining gas/magma distribution coefficients and show that Earth's subsolar Si/Mg ratio may be due to loss of a primordial steam atmosphere. We conclude that hot rocky exoplanets that are undergoing or have undergone escape of steam-bearing atmospheres may experience fractional vaporization and loss of Si, Mg, Fe, Ni, Al, Ca, Na, and K. This loss can modify their bulk composition, density, heat balance, and interior structure
A comparison of chemistry and dust cloud formation in ultracool dwarf model atmospheres
The atmospheres of substellar objects contain clouds of oxides, iron,
silicates, and other refractory condensates. Water clouds are expected in the
coolest objects. The opacity of these `dust' clouds strongly affects both the
atmospheric temperature-pressure profile and the emergent flux. Thus any
attempt to model the spectra of these atmospheres must incorporate a cloud
model. However the diversity of cloud models in atmospheric simulations is
large and it is not always clear how the underlying physics of the various
models compare. Likewise the observational consequences of different modeling
approaches can be masked by other model differences, making objective
comparisons challenging. In order to clarify the current state of the modeling
approaches, this paper compares five different cloud models in two sets of
tests. Test case 1 tests the dust cloud models for a prescribed L, L--T, and
T-dwarf atmospheric (temperature T, pressure p, convective velocity
vconv)-structures. Test case 2 compares complete model atmosphere results for
given (effective temperature Teff, surface gravity log g). All models agree on
the global cloud structure but differ in opacity-relevant details like grain
size, amount of dust, dust and gas-phase composition. Comparisons of synthetic
photometric fluxes translate into an modelling uncertainty in apparent
magnitudes for our L-dwarf (T-dwarf) test case of 0.25 < \Delta m < 0.875 (0.1
< \Delta m M 1.375) taking into account the 2MASS, the UKIRT WFCAM, the Spitzer
IRAC, and VLT VISIR filters with UKIRT WFCAM being the most challenging for the
models. (abr.)Comment: 22 pages, 17 figures, MNRAS 2008, accepted, (minor grammar/typo
corrections
Disequilibrium Carbon, Oxygen, and Nitrogen Chemistry in the Atmospheres of HD 189733b and HD 209458b
We have developed 1-D photochemical and thermochemical kinetics and diffusion
models for the transiting exoplanets HD 189733b and HD 209458b to study the
effects of disequilibrium chemistry on the atmospheric composition of "hot
Jupiters." Here we investigate the coupled chemistry of neutral carbon,
hydrogen, oxygen, and nitrogen species, and we compare the model results with
existing transit and eclipse observations. We find that the vertical profiles
of molecular constituents are significantly affected by transport-induced
quenching and photochemistry, particularly on cooler HD 189733b; however, the
warmer stratospheric temperatures on HD 209458b can help maintain
thermochemical equilibrium and reduce the effects of disequilibrium chemistry.
For both planets, the methane and ammonia mole fractions are found to be
enhanced over their equilibrium values at pressures of a few bar to less than a
mbar due to transport-induced quenching, but CH4 and NH3 are photochemically
removed at higher altitudes. Atomic species, unsaturated hydrocarbons
(particularly C2H2), some nitriles (particularly HCN), and radicals like OH,
CH3, and NH2 are enhanced overequilibrium predictions because of quenching and
photochemistry. In contrast, CO, H2O, N2, and CO2 more closely follow their
equilibrium profiles, except at pressures < 1 microbar, where CO, H2O, and N2
are photochemically destroyed and CO2 is produced before its eventual
high-altitude destruction. The enhanced abundances of HCN, CH4, and NH3 in
particular are expected to affect the spectral signatures and thermal profiles
HD 189733b and other, relatively cool, close-in transiting exoplanets. We
examine the sensitivity of our results to the assumed temperature structure and
eddy diffusion coefficientss and discuss further observational consequences of
these models.Comment: 40 pages, 16 figures, accepted for publication in Astrophysical
Journa
TRPV1 in Brain Is Involved in Acetaminophen-Induced Antinociception
Background: Acetaminophen, the major active metabolite of acetanilide in man, has become one of the most popular overthe- counter analgesic and antipyretic agents, consumed by millions of people daily. However, its mechanism of action is still a matter of debate. We have previously shown that acetaminophen is further metabolized to N-(4-hydroxyphenyl)-5Z,8Z,11Z,14Z-eicosatetraenamide (AM404) by fatty acid amide hydrolase (FAAH) in the rat and mouse brain and that this metabolite is a potent activator of transient receptor potential vanilloid 1 (TRPV1) in vitro. Pharmacological activation of TRPV1 in the midbrain periaqueductal gray elicits antinociception in rats. It is therefore possible that activation of TRPV1 in the brain contributes to the analgesic effect of acetaminophen. Methodology/Principal Findings: Here we show that the antinociceptive effect of acetaminophen at an oral dose lacking hypolocomotor activity is absent in FAAH and TRPV1 knockout mice in the formalin, tail immersion and von Frey tests. This dose of acetaminophen did not affect the global brain contents of prostaglandin E-2 (PGE(2)) and endocannabinoids. Intracerebroventricular injection of AM404 produced a TRPV1-mediated antinociceptive effect in the mouse formalin test. Pharmacological inhibition of TRPV1 in the brain by intracerebroventricular capsazepine injection abolished the antinociceptive effect of oral acetaminophen in the same test. Conclusions: This study shows that TRPV1 in brain is involved in the antinociceptive action of acetaminophen and provides a strategy for developing central nervous system active oral analgesics based on the coexpression of FAAH and TRPV1 in the brain
Model of the complex of Parathyroid hormone-2 receptor and Tuberoinfundibular peptide of 39 residues
<p>Abstract</p> <p>Background</p> <p>We aim to propose interactions between the parathyroid hormone-2 receptor (PTH2R) and its ligand the tuberoinfundibular peptide of 39 residues (TIP39) by constructing a homology model of their complex. The two related peptides parathyroid hormone (PTH) and parathyroid hormone related protein (PTHrP) are compared with the complex to examine their interactions.</p> <p>Findings</p> <p>In the model, the hydrophobic N-terminus of TIP39 is buried in a hydrophobic part of the central cavity between helices 3 and 7. Comparison of the peptide sequences indicates that the main discriminator between the agonistic peptides TIP39 and PTH and the inactive PTHrP is a tryptophan-phenylalanine replacement. The model indicates that the smaller phenylalanine in PTHrP does not completely occupy the binding site of the larger tryptophan residue in the other peptides. As only TIP39 causes internalisation of the receptor and the primary difference being an aspartic acid in position 7 of TIP39 that interacts with histidine 396 in the receptor, versus isoleucine/histidine residues in the related hormones, this might be a trigger interaction for the events that cause internalisation.</p> <p>Conclusions</p> <p>A model is constructed for the complex and a trigger interaction for full agonistic activation between aspartic acid 7 of TIP39 and histidine 396 in the receptor is proposed.</p
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